The analysis of nucleic acids is indispensable in life science research. Roche Applied Science provides a wide variety of kits and reagents for labeling and detecting nucleic acids.
- Labeling
Create a specific probe directed against the sequence of interest when localizing or quantifying the expression of a specific gene target. Probes previously labeled using radioactivity, are labeled using digoxigenin for chemiluminscent, fluorescent, or colorimetric detection. - Detection
Probe by Southern blotting, dot blotting, northern blotting, array analysis, colony hybridization, in situ hybridization and ELISA using sensitive labeled probes. Target-specific signals are captured using autoradiographic films or image acquisition systems. - Hybridization
Many factors influence the hybridization of probe to target. Benefit from proven Roche methods and see the results in your research using nucleic acid labeling and detection for hybridization using the DIG System. - The DIG System - Nonradioactive Labeling and Detection of Nucleic Acids
Roche's nonradioactive technology allowed customers to move away from using radioactive isotopes. After 15 years, the DIG System remains the nonradioactive alternative of choice for labeling and detecting nucleic acids for both filter hybridization and in situ hybridization.