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Press Releases
15 May 2012
BGI Installs Roche GS FLX+ System to Enhance Long Read Sequencing Capabilities for Genome and Transcriptome Research
BGI, one of the worlds largest genomics organizations, announced today that a new Roche GS FLX+ System has been successfully installed at its facility in Shenzhen, China.
More09 May 2012
Roche 454 Life Sciences and SoftGenetics Sign Co-Promotion Agreement for Next-Gen Sequencing Software Tools
454 Life Sciences, a Roche Company, and SoftGenetics announced today that the two firms have entered into a co-promotion agreement designed to provide users of 454 Sequencing Systems the broad range of next-generation sequencing data analysis options provided by SoftGenetics NextGENe® software.
More24 April 2012
Roche Launches 454 Sequencing Assays for High Sensitivity Genetic Variant Detection in Leukemia Samples to Drive Blood Cancer Research Worldwide
Roche announced today the launch and immediate availability of the GS GType TET2/CBL/KRAS and the GS GType RUNX1 Primer Sets for comprehensive genetic variation detection in four key human genes using the companys 454 GS Junior and GS FLX Systems.
More16 April 2012
Roche Launches Software Upgrade for GS Junior System, Announces Long Read Improvements and Workflow Automation for 2012/2013
Roche announced today the immediate availability of a new software upgrade and further upcoming sequencing performance and workflow improvements to the company's 454 GS Junior System.
More28 March 2012
xCELLigence System Evaluated in EU Project to Replace Animal Experiments in Cosmetics Industry
Roches xCELLigence RTCA System is being used in the European Unions SEURAT (Safety Evaluation Ultimately Replacing Animal Testing) initiative to run five years from 2011 to 2016.
More14 March 2012
Spanish Research Team Uses Roche's GS FLX+ System to Sequence Antibiotic Resistance Bacteria in Recent Hospital Outbreak
A team of researchers from the Hospital Universitario La Paz Research Institute (IdiPAZ, Madrid), LifeSequencing S.L. (Valencia), Era7 Bioinformatics (Madrid) and Roche Spain (Barcelona) announced today the sequencing of the whole genome of three antibiotic resistant strains of Klebsiella pneunomiae isolated from a recent outbreak in a Spanish hospital.
More29 February 2012
Roche's MagNA Pure LC 2.0 System for Monitoring DNA in Therapeutic Proteins and Monoclonal Antibody Drugs
To ensure product safety, clearance of host-cell DNA is essential when manufacturing therapeutic proteins and monoclonal antibody (mAB) drugs. Using the MagNA Pure LC 2.0 System from Roche, scientists have developed and validated an automated process for monitoring clearance of Chinese hamster ovary (CHO) cell DNA during the capture and polishing steps when processing therapeutic proteins and mAB drugs (1).
More22 February 2012
TATAA Biocenter Expands Offerings using Roche´s RealTime ready Custom qPCR Assays and Panels
TATAA Biocenter, Europe´s leading provider of genomic services using quantitative real-time polymerase PCR (qPCR), is expanding its offerings to high-throughput gene expression profiling using Roche´s RealTime ready Custom qPCR Assays and Panels.
More15 February 2012
New Findings in Drug-Induced Receptor Activity Using Roche's xCELLigence System
A research team led by Dr. Michel Bouvier at the Institute for Research in Immunology and Cancer (IRIC) of the University of Montreal in Quebec, used the Roche xCELLigence SP Instrument to measure changes in cell response following ligand stimulation (Stallaert et al., 2012, PloS ONE 7(1): e29420).
More09 February 2012
Roche's xCELLigence Cardio Instrument Used to Detect Beating Rhythm and Proarrhythmic Effects of Compounds in Stem Cell-Derived Cardiomyocytes
In an effort to improve preclinical cardiotoxicity assays, reduce drug testing attrition rates, and ensure drug safety, collaborating scientists at the University Medical Center Utrecht in the Netherlands, and Bioscience Department of AstraZeneca R&D, Mölndal, Sweden, have tested Roche's xCELLigence Cardio Instrument.
More08 February 2012
Roche Supports the Smithsonian's National Zoo with Next-Generation Sequencing Instrument for Animal Conservation Research
Roche and the Smithsonian Conservation Biology Institute in Washington, DC announced today a collaboration agreement to use Roche's GS Junior benchtop sequencing system for research in SCBI's Center for Conservation and Evolutionary Genetics
More31 January 2012
Roche Diagnostics Announces Dan Zabrowski as New Head of Roche Applied Science
As of February 1, 2012, Dan Zabrowski is Head of Roche Applied Science in the Diagnostics Division, located in Penzberg, Germany. He succeeds Paul Brown who has led Roche Applied Science since September 2011. Dan Zabrowski will report to Daniel O'Day, COO Roche Diagnostics
More30 January 2012
Hamilton Introduces Automated DNA Sample Enrichment Solution using Roche 454 REM e System
Hamilton Robotics announced today a new automated solution for DNA sample enrichment on the MICROLAB STARlet Liquid Handling Workstation. Integrating Roche's REM e liquid handling system, the workflow solution enriches up to eight DNA samples for subsequent sequencing on the GS FLX System.
More17 January 2012
Roche´s GS Junior Sequencing System Used in Research on Personalized Tumor Treatment
The Center for Human Genetics and Laboratory Medicine Dr. Klein and Dr. Rost, and IMGM Laboratories, both located in Martinsried Germany, reported using the Roche GS Junior Benchtop System to sequence clinically relevant exons and identify genomic variations in solid tumors treated with an antibody-based medicine.
More12 January 2012
Roche's Sequence Capture Technology Used to Identify SMPX Mutations Underlying Human Hereditary Hearing Loss
Hereditary hearing loss is the most common sensory disorder in humans. A German research team led by Ingo Kurth from the Institute of Human Genetics at the University Hospital Jena, Germany, used a number of different methods, including Roche's NimbleGen Custom Sequence Capture 385K array to identify the gene mutated in the disease locus of the X-chromosome of a Spanish family with hereditary hearing loss (1).
More28 November 2011
Roche NimbleGen and BGI Develop Advanced MHC Region Capture Technology for Human Disease and Biomedical Research
Roche NimbleGen, Inc. and BGI, the world's largest genomic organization, announced that they have developed a Major Histocompatibility Complex (MHC) region capture technology based on NimbleGen SeqCap EZ Choice Library, a revolutionary process for the enrichment of the MHC region.
More11 Oktober 2011
Roche Licenses Nanopore Sequencing Technologies from Arizona State University and Columbia University for Rapid, Affordable DNA Sequencing
Roche (SIX: RO, ROG; OTCQX: RHHBY) and Arizona Technology Enterprises (AzTE) announced today an agreement to license several technologies developed by Dr. Stuart Lindsay at the Biodesign Institute at Arizona State University and Dr. Colin Nuckolls of the Columbia University Nanoscience Center for the development of a revolutionary DNA sequencing system.
More10 Oktober 2011
Roche NimbleGen Announces New Pre-capture Multiplexing for Target Enrichment Technology in Sequencing
With the decreasing cost and increasing throughput of sequencing, researchers require a high-performance, cost-effective sample preparation pipeline for targeted sequencing.
More22 September 2011
Roche Researchers Sequence Complete Genome of Cynomolgus Monkey and Develop Novel Gene Expression Microarray for Drug Safety Assessment
A team of researchers from Roche (SIX: RO, ROG; OTCQX: RHHBY), including scientists from Roche Pharma Research and Early Development and Roche NimbleGen, reported in Genome Research (1) that they have generated the first draft genome sequence of the cynomolgus monkey (Macaca fascicularis) and developed a novel microarray design for in depth expression profiling for use in preclinical drug safety research.
More15 September 2011
Roche`s xCELLigence System Monitors Beating Periodicity of Stem Cell Derived Cardiomyocytes in Preclinical Safety Assessment
Cardiac toxicity is a major concern in drug development and it is imperative that clinical candidates are thoroughly tested for adverse effects earlier in the drug discovery process.
More06 September 2011
Erasmus University Medical Centre in Rotterdam Adopts Automated Target Enrichment Solution from Roche NimbleGen and Caliper Life Sciences for 3,000 Sample Exome Study
The Genetic Laboratory of the Department of Internal Medicine at Erasmus University Medical Centre in Rotterdam has adopted the combined automated target enrichment solution from Roche (SIX: RO, ROG; OTCQX: RHHBY) and Caliper Life Sciences.
More01 September 2011
Roche Launches Cedex Bio Bioprocess Analyzer for Reliable Metabolite Profiling and Substrate Analysis in Biotherapeutics Manufacturing
A vast majority of biotherapeutics are manufactured in either bacterial or mammalian expression systems. Metabolite profiling and substrate analysis during the fermentation process is critical to ensure optimal conditions for production and will trigger actions such as feed, improvement of oxygenation, adjustment of pH etc.
More24 August 2011
The Roy J. Carver Center for Genomics (CCG) Achieves Certified Service Provider status for Roche NimbleGen microarrays
In May 2011, The University of Iowa, Roy J. Carver Center for Genomics (CCG), entered into an agreement with Roche NimbleGen to provide microarray services through the Roche NimbleGen Certified Service Provider (CSP) program.
More18 August 2011
Medicinal Genomics Sequences the Cannabis Genome Using Roche's GS FLX+ System
Medicinal Genomics, a private company headquartered in Marblehead, Mass., USA and the Netherlands, announced today that it has sequenced the entire genomes of Cannabis sativa and Cannabis indica, representing two strains of the therapeutic plant.
More18 August 2011
Roche and PerkinElmer Enter into New Agreement for Distribution of NimbleGen CGX Cytogenetics Array Workflow
Roche (SIX: RO, ROG; OTCQX: RHHBY) and PerkinElmer (NYSE: PKI) today announced a new supply agreement for distribution of the NimbleGen CGX microarray workflow, for use in constitutional disease research.
More11 August 2011
Researchers Decode Genome of Atlantic Cod Using 454 Sequencing Systems
In a study published online this week in Nature, an international team of researchers report the first complete sequence of the Atlantic cod genome and an unexpected discovery of the unique immune system of this important fish species.
More28 July 2011
Roche's xCELLigence MP Instrument Used in the First Human Kinome Screen for Dynamic RNA Inhibitor Phenotypes during Cell Proliferation
RNA interference studies are a powerful technology for high-throughput screening. However, endpoint analyses only provide a snapshot of the analyzed cellular phenotype, as it is not possible to measure developmental changes over time.
More21 July 2011
Roche's xCELLigence RTCA Cardio Instrument Used to Estimate the Risk of Drug-induced Proarrhythmia in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
Cardiotoxicity, which results when drugs adversely affect the heart, explains why roughly one third of new pharmaceuticals are withdrawn from the market and why many compounds fail in late-stage clinical testing.
More20 July 2011
Roche's Cellavista System Performs Cell Analytics for a Novel Automated High Throughput Cell Culture Platform for Regenerative Medicine
Regenerative medicine is dependent on advances in tissue engineering, biochemistry and applied bioengineering to develop and produce cells and cell-based products that regenerate or repair damaged and degenerated tissues and organs.
More14 July 2011
Roche Announces Thomas Schinecker as New President of 454 Life Sciences
454 Life Sciences, a center of excellence of Roche's (SIX: RO, ROG; OTCQX: RHHBY) business unit Applied Science, and developer of the innovative GS Junior and GS FLX+ Systems for highthroughput DNA sequencing, announced that effective August 1, 2011, Dr. Thomas Schinecker is appointed Lifecycle Leader for Sequencing and President of 454 Life Sciences, Inc., in Branford, Connecticut, USA, reporting to Robert Yates, Head of Applied Science.
More12 July 2011
Roche NimbleGen and Caliper Collaborate to Offer Automated Target Enrichment Pipeline Solution for Next-Generation Sequencing
Roche (SIX: RO, ROG; OTCQX: RHHBY) and Caliper Life Sciences, Inc. (NASDAQ: CALP) today announced a co-marketing agreement for the development and optimization of automated protocols for the NimbleGen SeqCap EZ Library solution-based capture method for Caliper's Sciclone NGS Workstation.
More30 June 2011
Roche Applied Science Launches the Ultracompact LightCycler® Nano System Worldwide
With 'Size: Reduced. Fun: Amplified.', Roche Applied Science (SIX: RO, ROG; OTCQX: RHHBY) launched its new real-time PCR system on June 27th, 2011.
More29 June 2011
High throughput EHEC Pathogen Examination of Stool Samples using Roche's MagNA Pure 96 and LightCycler® Systems
During the last weeks, there has been a significant increase in the number of cases of bloody diarrhea associated with hemolytic-uremic syndrome (HUS) caused by enterohaemorrhagic Escherichia coli (EHEC).
More28 June 2011
Roche Launches GS FLX+ System Offering High-Quality, Sanger-like Reads with the Power of Next-Generation Throughput
454 Life Sciences, a Roche Company (SIX: RO, ROG; OTCQX: RHHBY), announced today the launch and immediate availability of the new GS FLX+ System, an instrument capable of generating extra-long sequencing reads up to 1,000 by in length.
More21 June 2011
Roche Diagnostics supports European Union's DETECTIVE Project to reduce Animal Testing
The xCELLigence RTCA System of Roche (SIX: RO, ROG; OTCQX: RHHBY) is being used in the European Union's DETECTIVE (Detection of endpoints and biomarkers for repeated dose toxicity using in vitro systems) Project, a joint study funded by the European Cosmetics Association (Colipa) and the European Commission, where Roche is a member of the consortium.
More16 June 2011
Roche's xCELLigence RTCA HT System: Fully-automated Measurement of Therapeutic Targets' Cellular Activity
High throughput, real time impedance-based secondary screening of Ox1 GPCR hits
More15 June 2011
Deadly E. Coli Strain Sequenced with Roche GS Junior System by HPA Scientists - Provides Community Most Complete Assembly to Date
The deadly E. coli O104 strain that has killed dozens and hospitalized thousands across Europe has been sequenced using 454 Life Sciences' benchtop GS Junior sequencing system to generate the "most accurate and detailed genetic analysis to date" of this particularly virulent strain.
More14 June 2011
Data Quality Meets Enjoyment: Roche's New Small LightCycler System Presented at Real-Time PCR Symposium in Prague
At the "Developments in Real-Time PCR" Symposium in Prague, June 13th - 17th http://www.qpcrsymposium.eu/, Roche (SIX: RO, ROG; OTCQX: RHHBY) officially presented the latest addition to the company's real-time PCR portfolio of LightCycler® instruments.
More09 June 2011
Agreement with Roche gives UCLA Stem Cell and Cancer Researchers Early Access to Leading-edge Technologies for the Advancement of Medical Research
An agreement between UCLA and Roche (SIX: RO, ROG; OTCQX: RHHBY) will provide stem cell and cancer researchers with leading-edge technologies that will drive research capabilities and further the understanding of complex disease.
More30 May 2011
Roche Applied Science and TIB Molbiol offer Assay Solution for Rapid EHEC Identification
With the recent outbreak in Europe of Enterohaemorrhagic Escherichia coli (EHEC), Roche Applied Science (SIX: RO, ROG; OTCQX: RHHBY) and TIB Molbiol are providing scientists with complementary technologies that can be used for the rapid identification and detection of EHEC.
More27 May 2011
Roche signs exclusive agreement with IT-IS Life Sciences Ltd on the new LightCycler® Nano Instrument for low-throughput qPCR market
Roche Applied Science (SIX: RO, ROG; OTCQX: RHHBY) has signed a worldwide exclusive OEM agreement with IT-IS Life Sciences Ltd for the distribution of the new LightCycler® Nano Instrument, which will complete the company's portfolio for the low throughput real-time PCR systems market (32-well format, 4x 8-tube strips).
More24 May 2011
454 Sequencing Systems Aid in Discovery of Novel Canine Hepatitis C Virus
In a study published online this week in the Proceedings of the National Academy of Sciences, researchers report the use of high-throughput sequencing technology to identify a novel hepatitis C virus in domestic dogs.
More12 May 2011
AgenoLAB Broadens Service Offering for Drug Development with Roche's RTCA Cardio Instrument
AgenoLAB, the Stuttgart-based service provider, is the first company in Germany to expand its service offering with the latest cell analysis technology from Roche (SIX: RO, ROG; OTCQX:RHHBY).
More10 May 2011
Electrical Impedance as a Novel Biomarker of Myotube Atrophy and Hypertrophy - Measured with Roche's xCELLigence System
Tracking physiological changes in skeletal muscle thickness is a direct and unbiased approach in screening therapeutic compounds that prevent skeletal muscle atrophy or induce hypertrophy.
More26 April 2011
BaseClear BV Certified to Provide NimbleGen Sequence Capture Services in The Netherlands
Roche NimbleGen, a Roche (SIX: RO, ROG; OTCQX: RHHBY) Company announced today that the Netherlands-based genomic service provider BaseClear BV has officially joined the Roche NimbleGen Certified Service Provider (CSP) Program.
More20 April 2011
Roche's RTCA HT Instrument Adapts Real-Time Cell Analysis to a High-Throughput Format
The new xCELLigence RTCA HT Instrument from Roche (SIX: RO, ROG; OTCQX: RHHBY) rounds out the Diagnostics Applied Science's portfolio in real-time cell analysis with a high-throughput product. The new instrument merges the power and flexibility of xCELLigence System technology with high-throughput analyses and workflows for automated screening applications.
More19 April 2011
Ambry Genetics Adds Certification of Roche NimbleGen CGH, DNA Methylation, Gene Expression, and ChIP-chip to Service Portfolio
Roche NimbleGen (SIX: RO, ROG; OTCQX: RHHBY) announces that Southern California (Aliso Viejo) based genomic services provider Ambry Genetics has officially become a Certified Service Provider (CSP) for NimbleGen Comparative Genomic Hybridization (CGH), Chromatin Immunoprecipiation-on-chip (ChIP-chip), DNA Methylation and Gene Expression.
More14 April 2011
Is lunar dust harmful to humans?
Roche's xCELLigence System used to investigate effects of lunar and Martian dust on mammalian skin
More11 April 2011
Roche and Lonza enter into MycoTOOL Distribution Agreement for Rapid Mycoplasma Testing Solutions
Roche (SIX: RO, ROG; OTCQX: RHHBY) and Lonza announced today that they have entered into a co-exclusive distribution agreement for the commercialization of Roche's MycoTOOL mycoplasma PCR assays.
More07 April 2011
MIT's Koch Institute to use Roche LightCycler® 480 System to help advance cancer research
Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the David H. Koch Institute for Integrative Cancer Research at MIT will be using the Roche LightCycler® 480 System, a real-time polymerase chain reaction (PCR) system for the analysis of gene expression and genetic variation, in advanced cancer research.
More06 April 2011
Roche Joins in Spanish Research Cooperation for Personalized Treatment of Hepatitis B and C
Roche Diagnostics (SIX: RO, ROG; OTCQX: RHHBY) is cooperating with the Spanish Vall d'Hebron Institute of Research (VHIR), the Networking Biomedical Research Centre in Liver and Digestive Diseases (CIBEREHD), and the software producer Advanced Biological Laboratories Therapy Edge Spain (ABL) in a study designed to resolve the current limitations that prevent the individualization of anti-HBV and anti-HCV (hepatitis B and C) treatments.
More05 April 2011
Roche and NuGEN Technologies Develop Whole Transcriptome Profiling Solution for 454 Sequencing Systems
454 Life Sciences, a Roche Company, and NuGEN Technologies, announced today the development of a unique sample preparation method and high-throughput sequencing solution for small and degraded RNA samples.
More31 March 2011
Roche Diagnostics Announces the Appointment of Robert Yates as New Head of Roche Applied Science
Roche Diagnostics (SIX: RO, ROG; OTCQX: RHHBY), announced today that effective from April 1, Robert Yates has been appointed as new Head of Roche Applied Science.
More30 March 2011
Roche Introduces Next-Generation HLA Typing Solution for 454 Sequencing Systems
454 Life Sciences, a Roche Company, announced today the launch and immediate availability of the new GS GType HLA Primer Sets for high- and medium-resolution genotyping of class I and class II loci of the Human Leukocyte Antigen (HLA) genes.
More29 March 2011
ATLAS Biolabs achieves Roche NimbleGen Certification for solution-based SeqCap EZ enrichment
Roche NimbleGen (SIX: RO, ROG; OTCQX: RHHBY) announces that ATLAS Biolabs GmbH, located in Berlin, Germany, has passed the certification process to qualify as a Roche NimbleGen Certified Service Provider (CSP) for SeqCap EZ enrichment.
More23 March 2011
A life sciences renaissance: 125th peer-reviewed publication enabled by xCELLigence System
To date, more than 125 peer-reviewed studies using Roche's (SIX: RO, ROG; OTCQX: RHHBY) xCELLigence System have been published, spanning a diverse group of applications, including cell invasion and migration of cancer cells (1), receptor activity assays (2), compound induced cytotoxicity (3), antibody-dependent cellular cytotoxicity (4), virus-mediated cytopathogenicity (5) and others (6).
More17 March 2011
Research Study Characterized Analytical Performance and Clinical Potential of Roche Flu Test
The availability of suitable diagnostic tools for identifying infected individuals is crucial for precise treatment in infectious diseases.
More16 March 2011
Using Roche's CASY Cell Counter and Analyzer for proliferation and viability measurement in cancer studies
In a recent study (1), Prokop et al. used the CASY Cell Counter and Analyzer from Roche Applied Science (SIX: RO, ROG; OTCQX: RHHBY) to identify the specific anticancer properties of a therapeutic substance in Burkitt-like lymphoma cells (BJAB cells).
More07 March 2011
Roche and RainDance Technologies Join Forces in Targeted Sequencing to Advance ADME Research
RainDance Technologies, Inc., and 454 Life Sciences, a Roche Company, today announced collaboration for the development and commercialization of a targeted next-generation sequencing (NGS) solution for simple and cost-effective investigation of drug absorption, distribution, metabolism, and excretion (ADME).
More17 January 2011
454 Life Sciences, University of Florida, and DOE JGI Sequence Sweet Orange Genome, Publish Annotated Assembly to Public Database
Researchers from the International Citrus Genomics Consortium announced this weekend at the Plant and Animal Genome (PAG) XIX conference in San Diego, California the availability of the sequence assembly and annotation of the first citrus genomes, the sweet orange (Citrus sinensis) and the Clementine mandarin (Citrus clementina).
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